In the quest for improved CVD prevention, Endothelial Function assessment has been proven to have unique clinical relevance. This is based on the following knowledge:

1. It is the earliest clinically detectable stage of CVD
2. Endothelial Dysfunction is a strong predictor of CV outcome
3. Reversing Endothelial Dysfunction significantly improves CV outcome

At the upcoming ACC Annual Scientific Sessions, Dr. Rubinshtein of the Mayo Clinic presented the incremental value of Endothelial Function to Framingham Risk Score (session details below). The joint study by investigators from Mayo Clinic and Tufts Medical Center, on 270 individuals, followed up for almost 6 years, used the Endo-PAT2000 device to assess Endothelial Function.Endo-PAT2000 is the only FDA-cleared device indicated for assessment of Endothelial Function.

Itamar Medical wishes to invite you to discuss how you can incorporate this noninvasive, easy-to-use device into your clinic’s workflow.

During the sessions there were 4 other presentations of studies with the Endo-PAT – details below.

Assessment of Endothelial Function by Peripheral Arterial Tonometry Predicts Cardiovascular Events Beyond the Framingham Risk ScoreRonen Rubinshtein, Jeffrey T. Kuvin, Morgan Soffler, Ryan J. Lennon, Rebecca E. Nelson, Geralyn M. Pumper, Lilach O. Lerman, Amir Lerman, Mayo Clinic, Rochester, MN, Tufts - New England Medical Center, Boston, MA Tuesday, Mar 31, 2009, 11:30 AM -11:45 AM, Oral Contribution 0917-7, Room W308C

Does Endothelial Dysfunction Contribute to Exercise Limitation in Heart Failure With Preserved Ejection Fraction?Barry A. Borlaug, Thomas P. Olson, Carolyn S.P. Lam, Kelly S. Flood, Bruce D. Johnson, Margaret M. Redfield, Amir Lerman, Mayo Clinic, Rochester, MN Sunday, Mar 29, 2009, 3:30 PM - 4:30 PM, Poster Contribution 1024-208, West Hall D

One Week of Clopidogrel Therapy Improves Endothelial Function in Subjects With Stable Coronary Artery Disease: A Randomized Control StudyLee-Jen Luu, Scott R. Willoughby, James D. Cameron, Adam J. Nelson, Stephen G. Worthley, Matthew I. Worthley, MonasHeart, Melbourne, Australia, Royal Adelaide Hospital, Adelaide, Australia Sunday, Mar 29, 2009, 9:30 AM -10:30 AM, Poster Contributions 1013-106, West Hall D

Differential Circadian Variation in Arterial Tone, Stiffness and Endothelial FunctionIbhar Al Mheid, Konstantinos Aznaouridis, Alanna Morris, Riyaz Patel, Nino Kavtaradze, Hamid Syed, Wayne Alexander, Arshed Quyyumi, Emory University, Atlanta, GA Monday, Mar 30, 2009, 9:30 AM -10:30 AM, Poster Contribution 1031-111, West Hall D

The Effect of Beta-Blockers on Ambulatory Arterial Stiffness Index and Wave Reflection in Patients With HypertensionKevin S. Heffernan, Ramya Suryadevara, Paula Mooney, Richard H. Karas, Jeffrey T. Kuvin, Tufts Medical Center, Boston, MA Monday, Mar 30, 2009, 11:15 AM -11:30 AM, Oral Contribution 0904-6, Room W308A