Itamar Medical Home  Products Endo-PAT2000
Endo-PAT2000
Prevention Magazine selects EndoPAT among Top Medical Breakthroughs of 2009 Watch EndoPAT on Totay's Health show Endothelial Function Assessment with Endo-PAT2000 Endo-PAT2000 System is a noninvasive method to evaluate endothelial function.Endo-PAT2000 adds an important dimension to cardiovascular prevention by enabling physicians to reliably measure endothelial function and identify pathological cases of endothelial dysfunction. Endothelial dysfunction is the earliest clinically detectable stage of cardiovascular disease.Endothelial Function Applications: Basic science and clinical researchPharmacological protocols - assessment of drug efficacy Primary prevention of Coronary Artery Disease (CAD) Implementation of clinical protocols for early diagnosis Evaluation of treatment protocols
Endo-PAT2000 is an easy to use, office-based device for assessing endothelial function. The PAT signal is recorded using Itamar Medical's, noninvasive, pneumatic, finger bio-sensor. The data recorded is analyzed automatically. Advanced Digital Signal Processing (DSP) algorithms and reports are available within seconds of completing the test.Endo-PAT2000 – Assessing Endothelial Function · Noninvasive
· Easy to use
· User independent
· Automatic data analysis
· Supports both clinical and research applications
· Reliable and reproducible results
· FDA cleared and CE marked
The medical community has long sought a cost-effective, reliable, and non-invasive method to detect endothelial dysfunction. A noninvasive technology that could accurately and reliably enhance the examination and follow-up for cardiac disease patients. Itamar Medical's Endo-PAT2000 is meeting this challenge, enhancing the traditional clinical settings’ diagnostic capabilities for endothelial dysfunction. The Endo-PAT2000 can be used in any setting, from hospital bedside to outpatient clinic.
Graph of normal endothelial function PAT signal tracings. The Endo–PAT2000 provides a very high degree of sensitivity and specificity as compared to the current Gold Standard of coronary artery endothelial function assessment – the coronary blood flow response to intra-coronary acetylcholine-infusion.
The Mayo Clinic’s Cardiology Center in Minnesota conducted a study in which 94 subjects underwent both an angiographic assessment of endothelial function in the coronaries and Endo-PAT examinations. The PAT RH index yielded a sensitivity of 82% and a specificity of 77% compared to intra-coronary endothelial function tests (see below). 
The first graph (left) demonstrates a ROC Curve for an Endo-PAT score of 1.67 as a threshold of endothelial dysfunction. The second bar-graph compares the intra-coronary and Endo-PAT endothelial function scores (right)
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Endo-PAT2000
Non-invasive assessment of endothelial function
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Watch-PAT200
Ambulatory diagnosis of sleep related breathing disorders
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EndoPAT Product Overview
EndoPAT on Today Show
